Interstitial high-dose-rate-brachytherapy in advanced esthesioneuroblastoma.
 

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11-19-08 08:44 AM
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Interstitial high-dose-rate-brachytherapy in advanced esthesioneuroblastoma.
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Interstitial high-dose-rate-brachytherapy in advanced esthesioneuroblastoma.

Laryngoscope. 2008 Nov;118(11):2006-10

Authors: Tselis N, Heyd R, Baghi M, Zamboglou N

Esthesioneuroblastoma is a rare neuroectodermal tumor of the nasal vault with an aggressive biological behavior that is characterized by local recurrence, atypical distant metastasis, and poor long-term prognosis. The treatment regimen consists of surgical resection, radiation therapy, and chemotherapy in various, mainly stage-dependent, combinations. We report two cases of primary metastatic and locally recurrent disease, which were treated with computed tomography-guided interstitial high-dose-rate brachytherapy in palliative and curative intent, respectively. Computed tomography-guided interstitial high-dose-rate brachytherapy should be considered as a feasible treatment option for advanced esthesioneuroblastoma.

PMID: 18641524 [PubMed - indexed for MEDLINE]