Bicyclononane Aldehydes and Antiproliferative Constituents from Amomum tsao-ko.
Planta Med. 2009 Feb 4;
Authors: Yang X, Küenzi P, Plitzko I, Potterat O, Hamburger M
A racemic mixture of a new bicyclononane aldehyde, (1 RS,5 SR,6 RS)-5-hydroxybicyclo[4.3.0]non-2-ene-2-carbaldehyde ( 1) was isolated from the fruits of AMOMUM TSAO-KO, together with 12 known compounds ( 2- 13). The structure of 1 was determined on the basis of extensive spectroscopic analysis, including 1D and 2D NMR data. The antiproliferative activity of compounds 1- 13 was assessed in the murine neuroblastoma cell line N2a.
PMID: 19194839 [PubMed - as supplied by publisher]