[Clinical analysis of 10 cases of olfactory neuroblastoma.]
 

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03-03-09 08:46 AM
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[Clinical analysis of 10 cases of olfactory neuroblastoma.]
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[Clinical analysis of 10 cases of olfactory neuroblastoma.]

Zhejiang Da Xue Xue Bao Yi Xue Ban. 2009 Jan;38(1):103-6

Authors: Wang HL, Fan GK, Lin ZH

OBJECTIVE: To review the diagnosis, treatment and prognosis of olfactory neuroblastoma. METHODS: Clinical data were retrospectively reviewed in 10 cases of olfactory neuroblastoma admitted from 1998 to 2002, including data of transmission electron microscopic (TEM) observation in 4 cases. According to Kadish's classification, 2 cases were in stage A, 4 in stage B and 4 in stage C. Three patients were treated with surgery alone, 7 with combined surgery and radiation. RESULT: Among 10 cases, the overall 5-year survival rate was 60 %(6/10); 3 patients died from local recurrence, 1 lost follow-up. TEM demonstrated granules in the cytoplasm of 3 patients. Conclusion: The combined surgery and radiation can achieve excellent local control. Transmission electron microscope is important for its diagnosis.

PMID: 19253437 [PubMed - in process]