New approaches to pharmacotherapy of tumors of the nervous system during childhood and adolescence.
 

Posts


Write a Post
03-26-09 08:27 AM
Anonymous
New approaches to pharmacotherapy of tumors of the nervous system during childhood and adolescence.
Reply
Related Articles

New approaches to pharmacotherapy of tumors of the nervous system during childhood and adolescence.

Pharmacol Ther. 2009 Jan 22;

Authors: Schor NF

Tumors of the nervous system are among the most common and most chemoresistant neoplasms of childhood and adolescence. Malignant tumors of the brain collectively account for 21% of all cancers and 24% of all cancer-related deaths in this age group. Neuroblastoma, a peripheral nervous system tumor, is the most common extracranial solid tumor of childhood, and 65% of children with this tumor have only a 10 or 15% chance of living 5 years beyond the time of initial diagnosis. Novel pharmacological approaches to nervous system tumors are urgently needed. This review presents the role of and current challenges to pharmacotherapy of malignant tumors of the nervous system during childhood and adolescence and discusses novel approaches aimed at overcoming these challenges.

PMID: 19318043 [PubMed - as supplied by publisher]