Fingering modulators of retinoic acid signaling identifies new prognostic marker for neuroblastoma.
Cancer Cell. 2009 Apr 7;15(4):249-51
Authors: Gronemeyer H, Zelent A
Properly designed genome-wide screening strategies can provide new insights into biological processes and/or biomarkers for malignant diseases. In this issue of Cancer Cell, Huang et al. demonstrate that the Krüppel zinc-finger protein ZNF423 is critical for retinoic acid signaling and is likely a favorable prognostic marker for neuroblastoma.
PMID: 19345323 [PubMed - in process]