Research Funding

The Children’s Neuroblastoma Cancer Foundation has funded more than $2.5 million in neuroblastoma research and programs. The following is an overview of the grants CNCF has provided.

Dr. John Maris, Principal Investigator – Children’s Hospital of Philadelphia, Texas Tech University Health Sciences Center, The Institute of Cancer Research, London, Seattle Children’s Hospital/Fred Hutchinson Cancer Center, The Icahn School of Medicine at Mount Sinai – Solving Indolent Neuroblastoma – a Multi-faceted, International Approach to Improve Survival

Dr. Elizabeth Sokol – Lurie Children’s Hospital, Chicago – to support their neuroblastoma research program

Dr. Jason Shohet – University of Massachusetts - Targeting TEAD4 transcription factor in high risk Neuroblastoma

Dr. Andras Heczey/Dr. Bilal Omer – Texas Children’s Hospital – Family support for families in clinical trial  T-cell therapy

Dr. Alice Yu – University of California, San Diego – support neuroblastoma research program

Dr. Paul Sondel – University of Wisconsin, Madison – support neuroblastoma research program

Dr. Darrell Yamashiro – Columbia University Medical Center – support neuroblastoma research program

Dr. Ami Desai – University of Chicago - New study evaluating how the micro biome influences neuroblastoma treatment.”

Dr. Xiao-Nan Li – Lurie Children’s Hospital, Chicago – support neuroblastoma research program

Dr. Ting Tao: Dana Farber Cancer Institute - The Role of ARID1A in neuroblastoma tumorigenesis

Dr. Bilal Omer: Baylor College of Medicine - Improving immune cell trafficking to neuroblastoma with “scout cells

Dr. Jason Shohet: Baylor College of Medicine - Analysis of p53 responses and regulation by G-CSFin neuroblastoma cancer stem cell subpopulations.

Dr. Julie Park: Seattle Children’s Hospital - MIBG Scoring Project: COGA3973 and SIOPEN-NBL-1

Dr. Sam Volchenboum: Comer Children’s Hospital - “The MYCN Oncogene: Providing Insight to Improved Diagnostic Stratification, Therapeutic Evaluation, and Novel Treatment Design for High-Risk Neuroblastoma."

NANT

SIOPEN

Travel grant for MIBG Scoring Project

MIBG Scoring Project: COGA3973 and SIOPEN-NBL-1

Dr. Susan Cohn, University of Chicago - Interactive International Neuroblastoma Information Network

Dr. Susan Cohn, University of Chicago - Genome-wide Analysis of Favorable Stage Neuroblastoma with MYCN Amplification

Dr. Nai-Kong Cheung, Memorial Sloan Kettering - Humanized 3F8 Research

Dr. Heidi Russell, Texas Children’s Hospital - Pepi Trial

Metin Gurcan PhD, Ohio State University - Computer aided prognosis of Neuroblastoma - 2-year grant

Dr. Kelly Goldsmith, Children’s Hospital of Philadelphia - Polymine Depletion Strategies in Neuroblastoma - 2-year grant

Dr. Eugene Kim, Baylor College of Medicine - The Role of MDM2 in Tumor Angiogenesis in Neuroblastoma - 2-year grant

Dr. Hong Xu, Memorial Sloan Kettering - B7H3: An Immunological Target for Neuroblastoma - 2-year grant

Dr. Barry Mauerer, Texas Tech University - Purchase of Fenretinide

Drs. Seeger/Reynolds, Children’s Hospital LA - Private donation

Dr. Susan Cohn, University of Chicago - Genome-wide Analysis of Favorable Stage Neuroblastomas with MYCN Amplification

Dr. Cynthia van Golen, Delaware State University - Therapeutic Efficacy of Agents Targeting the IGF-IR in HumanNeuroblastoma - 2-year grant

Dr. Elizabeth Beierle, University of Florida/ University of Alabama, Birmingham - Focal Adhesion Kinase and Vascular Endothelial Growth Factor Receptor-3 in Neuroblastoma - 2-year grant

Dr. Tasnim Ara, Children’s Hospital Los Angeles - Contribution of Bone Marrow Microenvironment to Neuroblastoma Chemoresistance and Tumor Progression - 2-year grant

Dr. Alexandre Chlenski, University of Chicago - SPARC-derived peptides for the treatment of Neuroblastoma - 2-year grant

Dr. Kristina Cole, Children’s Hospital of Philadelphia - siRNA Inhibition of the Protein Kinome in Neuroblastoma - 2-year grant

Dr. Nai-Kong Cheung, Memorial Sloan Kettering

Sonia Hernandez, Columbia University - Notch Signaling Pathway and VEGF Blockade in Neuroblastoma - 2-year grant

Dr. Jason Shohet, Baylor College of Medicine - MYCN-regulated MicroRNA Expression in Neuroblastoma - 2-year grant

Drs. Seeger/Reynolds, Children’s Hospital of Los Angeles - Private donation

Dr. Edward Attiyeh, Children’s Hospital of Philadelphia -Genetic basis of aggressive neuroblastoma - 2-year grant

Dr. Louis Chesler, University of CA, San Francisco - Proteomic analysis of serum from children with Neuroblastoma - 2-year grant

Dr. Radoslaw Zagoadzon, Beth Israel Deaconess - Studies on the role of CHK Kinase on Neuroblastoma - 2-year grant

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